Best Presentation Award Winners 2016

JSI gives an award to the superior presenters in the workshop and poster session of the JSI Annual Meeting.
Two awardees are selected in an each category by workshop coordinators and chairpersons.
This award is supported by BioLegend, Tomy Digital Biology and Sanofi.

Category-1: Hematopoiesis and Immune Environment
Local function of the IL-15 niche in thymus
Guangwei Cui (Kyoto University)
An organ-wide transcriptome of collagen-producing cells identifies the core signature of steady-state murine fibroblasts
Shigeyuki Shichino (The University of Tokyo, AMED)

Category-2: B cells
Dynamics of IRF4-dependent gene activation and repression during plasma cell differentiation
Kyoko Ochiai (Tohoku University School of Medicine, AMED-CREST)
LRRK1 controls B-cell responses by regulating CARMA1-dependent NF-κB activation
Keiko Morimoto (Osaka University)

Category-3: T cells
Timing and duration of MHC-I positive selection signals in the thymus reveal a novel compensatory signaling mechanism that prevents lineage fate errors
Motoko Kimura (Chiba University)
Membrane lipid binding by SH2 domains of Lck and Zap70 regulates T cell receptor activation
You-Me Kim (Pohang University of Science and Technology)

Category-4: Helper T cells
Gai-coupled non-canonical Hedgehog signaling in human Naive CD4 T lymphocytes.
Olga Elisseeva (Okinawa Institute of Science and Technology Graduate University)
The microRNA-183/96/182 cluster promotes T helper 17 cell pathogenicity by negatively regulating transcription factor Foxo1 expression
Kenji Ichiyama (Osaka University, Children's National Medical Center)

Category-5: Regulatory T cells
Soluble form of CTLA-4 produced by regulatory T cells facilitates M2 macrophage differentiation in auto-inflammatory condition.
Motonao Osaki (Kyoto University, Osaka University)
Immunological significance of dual secretion of TGF-β3 and IL-10 from regulatory T cells
Toshihiko Komai (The University of Tokyo)

Category-6: Innate lymphocytes
Identification of an alternative developmental pathway of Va14+ NKT cells from double-negative thymocytes
Nyambayar Dashtsoodol (RIKEN-IMS, Mongolian National University)
IFN regulatory factor 2 controls ILC development by promoting PLZF+ILC progenitor generation.
Yohei Okubo (Shinshu University)

Category-7: Dendritic cells and macrophages
Single-cell RNA-seq reveals a novel dendritic cell-primed early progenitor population
Daisuke Kurotaki (Yokohama City University)
MafB is the primary regulator of complement component C1q
Michito Hamada (University of Tsukuba)

Category-10: Mast cells & granulocytes
A critical role of ceramide-CD300f interaction in septic peritonitis
Kumi Izawa (Juntendo University)
Basophil-selective tryptase mMCP-11 plays crucial roles in the development of IgE-mediated chronic allergic inflammation in the skin.
Misako Iki (Tokyo Medical and Dental University)

Category-11: Allergy
The role of Tfh cells and DCs in particulate-induced iBALT formation in the lungs
Etsushi Kuroda (Osaka University, Health and Nutrition)
Clec10a suppresses Der f-induced immune response and dermatitis
Kazumasa Kanemaru (University of Tsukuba)

Category-12: Cytokines and chemokines
Regulation of IL-4 production in Group2 innate lymphoid cells
Yasutaka Motomura (RIKEN-IMS)
HBV-induced exosomal miRNAs down-regulate the expression of IL-21 mRNA by binding to its 3’UTR
Yutaka Enomoto (The University of Tokyo)

Category-13: Immunological memory
Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance
Shiki Takamura (Kindai University)
Molecular mechanisms for prevention of IgE-memory formation by membrane IgE
Kei Haniuda (Tokyo University of Science)

Category-14: Virus infection
Visualizing immune responses to influenza virus in mouse lung by using two-photon microscopy
Hiroshi Ueki (The University of Tokyo)
Modulation of the antiviral adaptor IPS-1-mediated innate immune responses by carboxylation
Tomohiko Okazaki (The University of Tokyo)

Category-15: Mycofungal/ parasite infection
Effect of Secreted Immunoglobulin Deficiency in Anti-Leishmania Immunity
Piyarat Srinontong (Gifu University)
Strategy of Zygomycete fungi to evade anti-fungal innate immunity
Masashi Kanayama (Duke University)

Category-16: Bacterial infection
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2
Kouyuki Hirayasu (Osaka University)
Recognition of mycobacterial lipid by Dendritic cell immunoactivating receptor
Kenji Toyonaga (Kagoshima University)

Category-17: Endogeneous innate immunity and inflammation
Involvement of RNAi accessory factors in MDA5/LGP2-mediated cellular responses by Cardiovirus infection
Akihiko Komuro (Niigata University)
Immune regulation through TRIM-regulated precision autophagy and secretion.
Tomonori Kimura (Osaka University)

Category-18: Mucosal-Skin Immunity
Commensal bacteria-derived metabolite induce colonic IgA producing cells
Junya Isobe (Keio University)
Immunization with GM-CSF-induced RALDH2-expressing dendritic cells induce antigen-specific IgA and Th responses in intestine
Naoki Takemura (Chiba University, The University of Tokyo)

Category-19: Tolerance and Immune suppression
Non-overlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
Baihao Zhang (Kyoto University, RIKEN-IMS)
Hepatic IL-10 producing CD11b+ macrophage recruited in colitic mice prevent T-cell-dependent hepatitis via gut-liver axis
Nobuhito Taniki (Keio University)

Category-20: Organ-specific autoimmune diseases
The anti-apoptotic effect of matrix metalloproteinase-2 suppresses streptozotocin-induced diabetes by activating the Akt signaling pathway
Kota Nishihama (Mie University)
Regulation of neuroinflammation by a cellular metabolite in experimental autoimmune encephalomyelitis
Daisuke Kamimura (Hokkaido University)

Category-21: Inflammatory arthritis
Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice
Takaichi Okano (Kobe University)
Histone lysine methylation and STAT3 differentially regulate constitutive nad IL-6-induced MMPs gene activation in rheumatoid arthritis synovial fibroblasts
Yasuto Araki (Saitama Medical University)

Category-22: Systemic autoimmune diseases
IL-21 enhances the development of autoimmune myositis via the production of GM-CSF from gd T cells
Takahiro Kageyama (Chiba University)
Cell-type-specific transcriptome analysis of peripheral blood mononuclear cells (PBMCs) revealed B cell contribution to systemic lupus erythematosus pathogenesis
Yusuke Takeshima (The University of Tokyo)

Category-23: Tumor immunity
IL-33 promotes obesity-associated liver cancer development
Fumitaka Kamachi (Tokyo University of Science)
A novel pathogenic role of interleukin-34 in cancer chemoresistance
Muhammad Baghdadi (Hokkaido University)

Category-24: Human Immunology (Immunointervention)
Gene Modules Correlated with Disease Activity and Abatacept Treatment Identified with Weighted Gene Co-Expression Network Analysis of CD4+ T Cell Subsets of Rheumatoid Arthritis
Shuji Sumitomo (The University of Tokyo)
Development of molecular targeted therapy for human acute GVHD in humanized mice
Genki Okumura (University of Tsukuba)

Category-25: Antigen presentation, Trafficking
HLA-F and MHC open conformer cooperate in antigen presentation during the inflammatory response
Akiko Ishitani (Nara Medical University)
Implications of Spns2-deficiency on S1P-driven lymphocytes egress, HEV-integrity and immunity.
Szandor Simmons (Osaka University)

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